Nexplanon®, 68 mg, implant for subdermal use is a radiopaque, non-biodegradable, progestagen-only, flexible implant preloaded in a sterile, disposable applicator.

Each radiopaque implant contains 68 mg of etonogestrel; the release rate is approximately 60-70 µg/day in week 5-6 and has decreased to approximately 35-45 µg/day at the end of the first year, to approximately 30-40 µg/day at the end of the second year and to approximately 25-30 µg/day at the end of the third year. The applicator is designed to be operated with one hand and to help facilitate correct subdermal insertion of the implant.

Indicated for contraception.

Safety and efficacy have been established in women between 18 and 40 years of age.

The HCP inserting or removing the device should be fully trained in the technique and should provide full counselling to the patient.